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A secret, high-tech struggle rages in neighborhoods everywhere between cats and dogs totally undiscovered by humans. This battle for world domination has been held in balance by an uneasy truce until now. Scientists have developed a vaccine that cures humans' allergies to dogs but not to cats and the cats must destroy it. A power-mad Persian, Mr. Tinkles, leads a massive feline attack on man's best friend, and crack canine agents spring into action to defeat the diabolical feline mastermind.